![]() ![]() Australasian experience and trials in sentinel lymph node biopsy: the RACS SNAC trial. Morbidity after sentinel lymph node biopsy in primary breast cancer: results from a randomized controlled trial. Purushotham AD, Upponi S, Klevesath MB, Bobrow L, Millar K, Myles JP, et al. Sentinel-lymph-node biopsy as a staging procedure in breast cancer: update of a randomised controlled study. Veronesi U, Paganelli G, Viale G, Luini A, Zurrida S, Galimberti V, et al. A Randomized clinical trial on sentinel lymph node biopsy versus axillary lymph node dissection in breast cancer: results of the Sentinella/GIVOM trial. Zavagno G, De Salvo GL, Scalco G, Bozza F, Barutta L, Del Bianco P, et al. Lymphatic mapping and sentinel node biopsy in the patient with breast cancer. Histopathologic validation of the sentinel lymph node hypothesis for breast carcinoma. Turner RR, Ollila DW, Krasne DL, Giuliano AE. Improved axillary staging of breast cancer with sentinel lymphadenectomy. Giuliano AE, Dale PS, Turner RR, Morton DL, Evans SW, Krasne DL. ![]() Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Giuliano AE, Kirgan DM, Guenther JM, Morton DL. Technical details of intraoperative lymphatic mapping for early stage melanoma. Morton DL, Wen D‑R, Wong JH, Economou JS, Cagle LA, Storm FK, et al. The evolution of sentinel node biopsy for breast cancer: personal experience. An approach for the treatment of penile carcinoma. Observations on a “sentinel node” in cancer of the parotid. Gould EA, Winship T, Philbin PH, Kerr HH. Turkish Federation of Breast Diseases Associations. The adventure of axillary treatment in early stage breast cancer. Recent advances in sentinel node biopsy in breast surgery. Clinical value of postoperative sentinel lymph node biopsy. He Z, Zhou Y, Wang F, Xu Q, Zhang W, Ni X, et al. ![]() Sentinel node biopsy for breast cancer: past, present, and future. Conclusionįurther research should be conducted to help resolve the clinical issues which are still debatable and to provide bases for improving the future trends which are progressing towards limiting the role of axillary dissection and axillary surgery to the minimum required level. They are all explained in the current article, in addition to the ongoing trials and the future aspects of SLNB in breast cancer. Many debates faced the researchers throughout the SLNB journey. This applies to specimen processing techniques as well. Various mapping techniques can be used for SLN localization, rendering oncology centers that have variable capabilities and preparations able to perform the procedure. ResultsĪdoption of sentinel lymph node biopsy as a standard axillary staging procedure was a marvelous trend that helped to decrease the complications of axillary dissection and significantly improve the quality of life of patients with breast cancer. We carried out a comprehensive literature review focusing on the journey of the use of sentinel lymph node biopsy (SLNB) in breast cancer from its start until its current station, including the variable clinical applications, the current debates, and the future issues. To be accepted as a standard of care, it had to pass successfully through a long journey which started in the early 1990s. Sentinel lymphadenectomy has replaced axillary lymph node dissection as a staging tool in early breast cancer. ![]()
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